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An assembly of capsid proteins (CA) form the mature viral core enclosing the HIV-1 ribonucleoprotein complex.Discrepant findings have been reported regarding the cellular sites and the extent of core disassembly (uncoating) in infected cells.Here, we combined single-virus imaging and time-of-drug-addition assays to read more elucidate the kinetic r

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IntroductionDegenerative joint disease (DJD) occurs very commonly in cats and can be associated with pain.Almost 70% of cats with DJD-associated pain suffer the co-morbidity of chronic kidney disease (CKD).There are currently very limited treatment or management options.A greater understanding of the systems biology of DJD, DJD-associated pain, and